MNI-coordinate Replication Issue
Posted: Wed Feb 17, 2016 10:47 pm
Hello,
I've been using Brain Anatomist to replicate a DTI study done in 2008 (A diffusion tensor imaging tractography atlas for virtual in vivo dissections by Catani & Thiebaut de Schotten). We registered brains to MNI-space using FSL's FLIRT software then opened the brains in Brain Anatomist, loaded from header and changed the reference to Talraich-MNI Template-SPM. The coordinates seemed to be correct (e.g. origin was at the anterior commissure).
Where I ran into trouble was using the MNI-coordinates described in the paper to define regions. The coordinates seemed to be misaligned by as much as 7 mm. I wanted to ask if there have been any changes to the software or the registration process since the paper was published that might explain some of this discrepancy. The authors used Brainvisa 3.02 for registration and SPM5 for normalization.
I would greatly appreciate any suggestions. We've hit a bit of a dead end now and aren't sure where to go from there so any thoughts or ideas would help tremendously.
Thanks,
Nick
I've been using Brain Anatomist to replicate a DTI study done in 2008 (A diffusion tensor imaging tractography atlas for virtual in vivo dissections by Catani & Thiebaut de Schotten). We registered brains to MNI-space using FSL's FLIRT software then opened the brains in Brain Anatomist, loaded from header and changed the reference to Talraich-MNI Template-SPM. The coordinates seemed to be correct (e.g. origin was at the anterior commissure).
Where I ran into trouble was using the MNI-coordinates described in the paper to define regions. The coordinates seemed to be misaligned by as much as 7 mm. I wanted to ask if there have been any changes to the software or the registration process since the paper was published that might explain some of this discrepancy. The authors used Brainvisa 3.02 for registration and SPM5 for normalization.
I would greatly appreciate any suggestions. We've hit a bit of a dead end now and aren't sure where to go from there so any thoughts or ideas would help tremendously.
Thanks,
Nick